Which OTC medicines (without a prescription) are most common—and what are their risks?

Author name: Admin Publication date: 2025-06-25 Article category: medicine

OTC Medicines in Germany: What are the most common—and are they safe without a prescription?
(OTC = Over-the-Counter = medicines sold without a prescription)

What does OTC mean?
OTC medicines can be purchased directly from a pharmacy or an online pharmacy without needing a prescription (rezeptfrei). They are allowed for over-the-counter sale because they are considered relatively safe for self-use—as long as instructions and dosage guidelines are followed.

Most common OTC medicines in Germany

Category Well-known medicines Common uses
Pain relief Ibuprofen, Paracetamol, ASA/ASS (Aspirin) Headache, fever, joint pain
Cold & flu Grippostad C, Wick MediNait, Nasal spray Common cold symptoms
Stomach & acid Iberogast, Rennie, Omeprazole (10 mg) Heartburn, bloating, mild ulcer-type discomfort
Mild calming aids Valerian, Neurexan, Lasea Stress, insomnia, mild anxiety
Herbal remedies Umckaloabo, Sinupret, GeloMyrtol Mild respiratory infections
Topical treatments Bepanthen, Fenistil, Voltaren Gel Inflammation, insect bites, muscle pain
Mild asthma Soolantra, Emsersalz inhalation Soothing inhalation/airway use
Antifungals Canesten, Lamisil Skin or foot fungus

Potential risks
Even though they are easy to buy, improper use can cause:

  • Liver damage from paracetamol overdose

  • Stomach bleeding from aspirin/ASS or ibuprofen with long-term use

  • Psychological dependence with mild sleep aids—even if they are herbal

  • Drug interactions (some stomach medicines may interact with heart or blood-pressure medications)

  • Allergic reactions (e.g., to menthol or plant extracts)

When should you avoid OTC medicines?

  • During pregnancy or breastfeeding (including herbal products)

  • For young children (especially under 6 years)

  • If you have chronic conditions (diabetes, heart disease, kidney disease, etc.)

  • If symptoms last longer than 3–5 days

Important advice
Even without a prescription, you can always ask a pharmacist for professional guidance before buying any OTC medicine. It’s also not recommended to order large quantities online without fully understanding proper use.


Editorial notice: The writers and editors at the website … strive to provide accurate information through extensive research and review of multiple sources. However, errors may occur or some information may be unconfirmed. Please treat the content as initial guidance and always consult the relevant authorities for verified information.

OTC Medicines in Germany: What are the most common—and are they safe without a prescription?(OTC = Over-the-Counter = medicines sold without a prescription)
What does OTC mean?OTC medicines can be purchased directly from a pharmacy or an online pharmacy without needing a prescription (rezeptfrei). They are allowed for over-the-counter sale because they are considered relatively safe for self-use—as long as instructions and dosage guidelines are followed.
Most common OTC medicines i...

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